RT Book, Section A1 Foreman, John W. A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 7044880 T1 Chapter 467. Diagnostic Approach to Renal Disease T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=7044880 RD 2024/04/16 AB The symptoms and signs of childhood renal disorders vary widely. Diagnostic clues are provided from the history, which should include a description of the amount, frequency, and color of the urine. Changes in any of these may herald a renal disease. The presence of symptoms such as pain on urination (dysuria), urgency (difficulty holding urine in the bladder), incontinence, or dribbling of the urinary stream in boys are also helpful. Pain is not typical of most renal diseases. However, flank pain is common with renal stones and pyelonephritis. Pain from renal stones is excruciating and often radiates from the flank toward the groin. Loin pain may occur with acute glomerulonephritis. Recurrent episodes of dehydration occur in disorders that affect water reabsorption or sodium retention such as tubular disorders, obstructive uropathy, and renal dysplasia. A history of maternal oligohydramnios suggests that in utero renal function was impaired. The family history is sometimes informative, especially in children with heritable kidney disorders such as Alport syndrome, hypercalciuria, cystinosis, and polycystic kidney.