RT Book, Section A1 Towbin, Jeffrey A. A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 7048643 T1 Chapter 489. Diseases of Myocardium T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=7048643 RD 2024/04/24 AB The myocardium can be affected by inflammatory (infectious or immune-mediated), metabolic, infiltrative, ischemic, or primary disease processes. These disorders may be inherited and may have significant overlap (eTable 489.1). Myocardial diseases may present acutely, with signs of congestive heart failure that include tachypnea, often with rales; tachycardia; an enlarged but quiet heart; soft heart sounds that may have a tic-tac rhythm; cardiac gallops; and either no murmurs or systolic murmurs of mitral or tricuspid regurgitation. Alternatively, they may present chronically with failure to thrive, decreased exercise tolerance, and more subtle findings of heart failure. Occasionally, the predominant process may be an arrhythmia, either atrial or ventricular tachycardia/fibrillation, or heart block. These present clinically with palpitations, syncope, or sudden death. The electrocardiogram and chest x-ray are useful in confirming the presence of heart disease, but are rarely diagnostic.