RT Book, Section
A1 Srivatsa, Abhinash
A1 Majzoub, Joseph A.
A2 Rudolph, Colin D.
A2 Rudolph, Abraham M.
A2 Lister, George E.
A2 First, Lewis R.
A2 Gershon, Anne A.
SR Print(0)
ID 7053090
T1 Chapter 525. Primary Disturbances in Water Homeostasis
T2 Rudolph's Pediatrics, 22e
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-149723-7
LK accesspediatrics.mhmedical.com/content.aspx?aid=7053090
RD 2024/04/19
AB Maintenance  of  the  tonicity  of  extracellular  fluids  within  a  very  narrow  range  is  crucial  for  proper  cell  function.  Normal  blood  tonicity  is  maintained  over  a  10-fold  variation  in  water  intake  by  a  coordinated  interaction  among  the  vasopressin,  thirst,  and  renal  systems.  Dysfunction  in  any  of  these  systems  can  result  in  abnormal  regulation  of  blood  osmolality,  which  if  not  properly  recognized  and  treated,  may  cause  life-threatening  hyperosmolality  or  hypoosmolality.1