RT Book, Section A1 Styne, Dennis M. A1 Cuttler, Leonna A2 Rudolph, Colin D. A2 Rudolph, Abraham M. A2 Lister, George E. A2 First, Lewis R. A2 Gershon, Anne A. SR Print(0) ID 7054632 T1 Chapter 540. Normal Pubertal Development T2 Rudolph's Pediatrics, 22e YR 2011 FD 2011 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-149723-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=7054632 RD 2024/03/29 AB Changes in hypothalamic-pituitary-gonadal endocrine function lead to the striking changes associated with secondary sexual development. Endocrine changes of puberty are divided into (1) gonadarche, or the awakening of gonadal action during which increased pituitary gonadotropins cause the secretion of gonadal steroids, and (2) adrenarche, or the awakening of adrenal androgen secretion caused by still undefined factors.