RT Book, Section
A1 Bergin, Ann M.
A2 Rudolph, Colin D.
A2 Rudolph, Abraham M.
A2 Lister, George E.
A2 First, Lewis R.
A2 Gershon, Anne A.
SR Print(0)
ID 7058086
T1 Chapter 563. Epilepsy Treatment: Ketogenic Diet and Neurostimulation
T2 Rudolph's Pediatrics, 22e
YR 2011
FD 2011
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-149723-7
LK accesspediatrics.mhmedical.com/content.aspx?aid=7058086
RD 2024/04/24
AB Most  children  with  epilepsy  in  childhood  achieve  seizure  freedom  with  anticonvulsant  medication,  and  many  outgrow  their  epilepsy  and  can  be  seizure-free  and  medication-free  in  adulthood.  However,  up  to  one  third  of  patients  can  have  intractable  epilepsy,  usually  defined  as  continuing  to  have  debilitating  seizures  despite  the  use  of  2  or  3,  appropriately  chosen  anticonvulsant  medications  at  high  therapeutic  doses.  For  some  children  who  have  focal  epilepsy,  surgical  resection  of  the  responsible  focus  offers  an  alternative  approach,  and  possibly  cure  of  epilepsy.  For  others  who  do  not  have  a  surgical  option,  dietary  manipulation  and  new  techniques  of  neurostimulation  offer  approaches  that  may  improve  or  even  achieve  seizure  control.  For  those  children  whose  seizure  control  improves,  a  reduction  in  medication  dose  or  number  can  improve  quality  of  life  by  reducing  adverse  effects.