RT Book, Section A1 Weinberg, Samuel A1 Prose, Neil S. A1 Kristal, Leonard SR Print(0) ID 6988156 T1 Section 13. Urticarial, Purpuric, and Vascular Reactions T2 Color Atlas of Pediatric Dermatology, 4e YR 2008 FD 2008 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-145543-5 LK accesspediatrics.mhmedical.com/content.aspx?aid=6988156 RD 2024/04/18 AB A wheal is an edematous papule that may enlarge to form a pink, sharply circumscribed, elevated plaque. The typical lesions of urticaria, pictured here, have a suggestion of central clearing. By definition, the individual lesions of urticaria evolve quickly and resolve within 24–48 hours. They are usually accompanied by severe pruritus. The most common etiologies of urticaria are medications, foods, and viral (Fig. 13-2) and bacterial infections. Autoimmune disease and malignancy are extremely rare causes. In the child with chronic urticaria, it is often difficult or impossible to identify a single cause.