RT Book, Section
A1 Weinberg, Samuel
A1 Prose, Neil S.
A1 Kristal, Leonard
SR Print(0)
ID 6988562
T1 Section 18. Drug Eruptions
T2 Color Atlas of Pediatric Dermatology, 4e
YR 2008
FD 2008
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-145543-5
LK accesspediatrics.mhmedical.com/content.aspx?aid=6988562
RD 2024/04/19
AB Diagnosing  drug  eruptions  has  become  a  common  experience  to  practitioners  in  all  branches  of  modern  medicine.  The  profusion  of  drugs  now  available,  the  continuous  influx  of  new  drugs,  and  the  capability  of  drugs  to  cause  actions  different  from  or  in  addition  to  their  pharmacologically  desirable  actions  make  adverse  cutaneous  reactions  an  inevitable  fact  of  modern  medical  practice.  The  kinds  of  cutaneous  reactions  are  varied.  Exanthems  (erythematous,  morbilliform  or  maculopapular),  urticaria,  fixed  drug  eruptions,  and  erythema  multiforme  are  the  most  common.  Figure  18-1  is  an  urticarial  reaction  from  Augmentin  and  Fig.  18-2  shows  a  morbilliform  eruption  from  ampicillin.  Constitutional  symptoms  of  low-grade  fever  and  malaise  may  be  associated  with  such  drug  eruptions.  Morbilliform  eruptions  from  ampicillin  are  more  frequently  seen  in  children  with  infectious  mononucleosis.