RT Book, Section A1 Weinberg, Samuel A1 Prose, Neil S. A1 Kristal, Leonard SR Print(0) ID 6988727 T1 Section 21. Neoplastic Diseases T2 Color Atlas of Pediatric Dermatology, 4e YR 2008 FD 2008 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-145543-5 LK accesspediatrics.mhmedical.com/content.aspx?aid=6988727 RD 2024/03/29 AB A dermal infiltrate of leukemic cells results in the papulonodular lesions, or plaques, that are illustrated here. Such primary involvement of the skin is relatively rare in childhood leukemia. The wide variety of secondary manifestations of leukemia includes petechiae and ecchymoses and pyoderma gangrenosum. A polymorphonuclear dermal infiltrate termed Sweet's syndrome (see Fig. 13-18) may be associated with leukemia. In addition, children receiving chemotherapy are prone to bacterial and fungal infections of the skin, severe varicella, and ulcerative or chronic herpes simplex.