RT Book, Section A1 Rahhal, Riad M. A2 Bishop, Warren P. SR Print(0) ID 55944886 T1 Chapter 7. Jaundice and Neonatal Cholestasis T2 Pediatric Practice: Gastroenterology YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-163379-6 LK accesspediatrics.mhmedical.com/content.aspx?aid=55944886 RD 2024/04/19 AB Jaundice comes from the French word “jaune,” meaning yellow. Jaundice refers to the yellow staining of the sclera, mucous membranes, and skin by bilirubin. It is not a disease by itself but rather a manifestation that accompanies different diseases. Jaundice is caused by elevated serum bilirubin levels with subsequent tissue deposition. In infants, it is usually apparent with bilirubin levels above 4–5 mg/dL (68–86 mmol/L). In older children, jaundice can be noted at levels above 2–3 mg/dL (34–51 mmol/L). The color of the sclera and skin varies depending on the serum bilirubin level. Jaundice involves the head first and progresses caudally with higher levels.