RT Book, Section A1 Sathanandam, Shyam K. A1 Fuller, Stephanie A1 Gillespie, Matthew J. A2 Gleason, Marie Murphy A2 Rychik, Jack A2 Shaddy, Robert SR Print(0) ID 56745948 T1 Chapter 5. Evaluation and Therapy: Neonatal Critical Heart Disease T2 Pediatric Practice: Cardiology YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-176320-2 LK accesspediatrics.mhmedical.com/content.aspx?aid=56745948 RD 2024/04/24 AB Critical heart disease in the newborn includes all congenital heart lesions that would result in neonatal demise unless immediate intervention is undertaken. It is estimated that congenital heart disease occurs in about 8 per 1000 live births.1 Not all congenital heart disease (CHD) presents in the newborn period. However, there are a handful of conditions that need immediate management in a newborn infant, the failure of which precludes survival. Roughly 3.5 in 1000 live births have critical CHD.1 Neonatal critical heart diseases can be broadly described as those that present as severe cyanosis (right heart obstruction) and those that present as shock (left heart obstruction). Table 5-1 lists common conditions in both categories. The common denominator to all critical heart diseases presenting in the neonatal period is that they need a patent ductus arteriosus for survival until further palliative procedures can be undertaken. To understand the physiology of these lesions, it is important to have knowledge of the circulatory changes that happen right after birth.