RT Book, Section A1 Glanzman, Marianne A1 Licht, Daniel A1 Wernovsky, Gil A2 Gleason, Marie Murphy A2 Rychik, Jack A2 Shaddy, Robert SR Print(0) ID 56747253 T1 Chapter 11. Neurodevelopment in Children with Complex Congenital Heart Disease T2 Pediatric Practice: Cardiology YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-176320-2 LK accesspediatrics.mhmedical.com/content.aspx?aid=56747253 RD 2024/03/29 AB Approximately 40,000 children are born in North America each year with congenital heart disease (CHD). Approximately half of these children require no therapy, because the defect is relatively minor (eg, a bicuspid aortic valve) or spontaneously heals (eg, a small ventricular septal defect). However, in the other half of these children, surgical or catheter intervention is necessary. For some of the children in this group, the CHD does not cause hypoxemia, circulatory insufficiency, or symptoms; these children typically undergo repair on an elective basis in childhood (eg, atrial septal defects or progressive valvar disease). In this group of school-age children, it has been shown that there is little to no impact on the central nervous system from either the unrepaired defect or from the effects of anesthesia, surgery, or postoperative care following the repair.1