RT Book, Section
A1 Bellarosa, Cristina
A1 Muchova, Lucie
A1 Vitek, Libor
A1 Tiribelli, Claudio
A2 Stevenson, David K.
A2 Maisels, M. Jeffrey
A2 Watchko, Jon F.
SR Print(0)
ID 56321714
T1 Chapter 4. Bilirubin Metabolism and Transport
T2 Care of the Jaundiced Neonate
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-176289-2
LK accesspediatrics.mhmedical.com/content.aspx?aid=56321714
RD 2024/04/25
AB Unconjugated  bilirubin  (UCB),  the  principal  mammalian  bile  pigment,  is  the  end  intravascular  product  of  heme  catabolism.  Like  many  weakly  polar,  poorly  soluble  compounds,  UCB  is  transported  in  blood  tightly  bound  to  albumin,  with  less  than  0.01%  of  total  bilirubin  circulating  in  an  unbound  form  (free  bilirubin  [Bf]).  This  fraction  governs  UCB  tissue  flux,  and  is  responsible  for  its  pathophysiological  effects  on  cells  and  tissues.