RT Book, Section A1 Maisels, M. Jeffrey A1 Stevenson, David K. A1 Watchko, Jon F. A1 McDonagh, Antony F. A2 Stevenson, David K. A2 Maisels, M. Jeffrey A2 Watchko, Jon F. SR Print(0) ID 56323435 T1 Chapter 10. Phototherapy and Other Treatments T2 Care of the Jaundiced Neonate YR 2012 FD 2012 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-176289-2 LK accesspediatrics.mhmedical.com/content.aspx?aid=56323435 RD 2024/04/19 AB We owe the development of clinical phototherapy to an astute observation made, more than 50 years ago, by Sister J. Ward, the nurse in charge of the premature baby unit at the former Rochford General Hospital in Essex, England.1 As described by Dobbs and Cremer, Sister Ward recognized the value of sunshine and fresh air to all, including premature babies, and she would take the “more delicate infants out into the courtyard, sincerely convinced that the combination of fresh air and sunshine would do them much more good than the stuffy, overheated atmosphere of the incubator.”1 During a ward round in 1956, Sister Ward showed the pediatricians a jaundiced, premature infant who appeared pale yellow except for a triangle of skin that was much yellower than the rest of the body. Apparently, a corner of the sheet had covered this part of the baby and the Sister recognized that the rest of the baby had been “bleached” by the sun. (It was only recognized more than a decade later that the mechanism for the bleaching of yellow serum and skin—photooxidation—probably plays a minor role in the reduction of the serum bilirubin concentration in newborns treated with phototherapy.)2,3