RT Book, Section A1 Keckler, Scott J. A1 Tuggle, David W. A2 Ziegler, Moritz M. A2 Azizkhan, Richard G. A2 Allmen, Daniel von A2 Weber, Thomas R. SR Print(0) ID 1100430928 T1 Renal Developmental Physiology and Pediatric Fluid and Electrolyte Management T2 Operative Pediatric Surgery, 2e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-162723-8 LK accesspediatrics.mhmedical.com/content.aspx?aid=1100430928 RD 2024/03/29 AB Fetal urine production begins at 10 to 13 weeks gestation, and although urine production increases thereafter throughout pregnancy, glomerular filtration rate (GFR) is always lower in preterm infants.Renal function changes quickly in the fetus and newborn with an increasing GFR and tubular maturity leading to enhanced concentrating ability.Calculation of maintenance fluid requirements is size dependent; however, practically, calculations are more typically based on body weight rather than body surface area.Premature infant fluid requirements are different from term infant requirements in both total fluid volumes and electrolyte content.To avoid serious neurologic injury, sodium abnormalities should not be corrected quickly.