RT Book, Section A1 Sømme, Stig A2 Ziegler, Moritz M. A2 Azizkhan, Richard G. A2 Allmen, Daniel von A2 Weber, Thomas R. SR Print(0) ID 1100431940 T1 Wound Healing T2 Operative Pediatric Surgery, 2e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-162723-8 LK accesspediatrics.mhmedical.com/content.aspx?aid=1100431940 RD 2024/10/15 AB Wound healing, like the body's response to injury, undergoes the three phases of inflammation, proliferation, and remodeling.Inflammatory cell infiltration is a key step in wound healing, stimulated in part by endothelial cells, monocytes and cytokines.The wound's fibrin plug brings collagen synthesizing fibroblasts to the wound, the cells that also stimulate the production of mucopolysaccharides.“Scarless” fetal wound healing may relate to an altered inflammatory response, collagen composition and hyaluronic acid composition when compared to adult wound healing and scar formation.Negative pressure is an important therapeutic adjunct for the treatment of delayed healing wounds.