RT Book, Section
A1 Rescorla, Frederick J.
A2 Ziegler, Moritz M.
A2 Azizkhan, Richard G.
A2 Allmen, Daniel von
A2 Weber, Thomas R.
SR Print(0)
ID 1100439320
T1 Teratoma
T2 Operative Pediatric Surgery, 2e
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-162723-8
LK accesspediatrics.mhmedical.com/content.aspx?aid=1100439320
RD 2024/04/24
AB Fifty  percent  of  pediatric  germ  cell  tumors  are  extragonadal.Teratomas  (mature  and  immature)  are  the  most  common  germ  cell  tumor  and  are  benign  lesions  requiring  only  complete  surgical  resection.Yolk  sac  (endodermal  sins)  is  the  predominant  prepubertal  malignant  histology  and  alpha  fetoprotein  (AFP)  is  a  marker  of  disease.Accurate  staging  is  essential  as  Stage  I  gonadal  tumors  are  treated  without  chemotherapy.The  survival  for  malignant  germ  cell  tumors  treated  with  surgery  and  selective  use  of  chemotherapy  is  excellent.Current  chemotherapy  is  extremely  effective,  thus  resection  of  adjacent  involved  organs  or  structures  is  not  indicated.Initially  unresectable  extragonadal  tumors  treated  with  neoadjuvant  chemotherapy  and  delayed  resection  have  equivalent  survival  compared  to  initial  resection.