RT Book, Section A1 Kappy, Michael S. A1 Allen, David B. A1 Geffner, Mitchell E. SR Print(0) ID 1102505594 T1 Diabetes Mellitus T2 Pediatric Practice: Endocrinology, 2e YR 2013 FD 2013 PB McGraw-Hill Education PP New York, NY SN 9780071813174 LK accesspediatrics.mhmedical.com/content.aspx?aid=1102505594 RD 2024/04/19 AB The majority of cases of diabetes mellitus falls into one of two categories: (1) type 1 diabetes, which is most commonly caused by autoimmune destruction of the pancreatic islet cells resulting in β-cell failure and an absolute deficiency of insulin (type 1 A diabetes, T1DM), and (2) type 2 diabetes (T2DM), which results from a combination of insulin resistance in target tissues and a lack of an adequate compensatory insulin response to overcome this resistance. The American Diabetes Association (ADA)1 recognizes more than 50 other specific types of diabetes (Table 11-1). All of these disorders collectively account for only 1% to 5% of cases of diabetes (see Part D of this chapter later on).