RT Book, Section A1 Miller, Emily R. A1 Allen, David B. A1 Ferry, Robert J. A2 Kappy, Michael S. A2 Allen, David B. A2 Geffner, Mitchell E. SR Print(0) ID 1102506029 T1 Hypoglycemia T2 Pediatric Practice: Endocrinology, 2e YR 2013 FD 2013 PB McGraw-Hill Education PP New York, NY SN 9780071813174 LK accesspediatrics.mhmedical.com/content.aspx?aid=1102506029 RD 2024/04/23 AB The transition from intrauterine to extrauterine life requires prompt adaptations to maintain glucose homeostasis. Increased rates of glucose utilization in infants and children compared to adults heighten dependency on coordinated glycogenolysis, gluconeogenesis, and fatty acid oxidation to prevent hypoglycemia during early life. Consequently, hypoglycemic disorders often present in the neonatal period or in infancy during transitions to longer feeding intervals. Since the brain during this time is particularly susceptible to injury due to glucose deprivation, prompt recognition and treatment of hypoglycemia is paramount.