RT Book, Section
A1 Lerner, Diana
A1 Werlin, Steven
A2 Goday, Praveen S.
A2 Mehta, Nilesh M.
SR Print(0)
ID 1105179493
T1 Nutrition in Acute Liver Failure and Acute Pancreatitis
T2 Pediatric Critical Care Nutrition
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-179852-5
LK accesspediatrics.mhmedical.com/content.aspx?aid=1105179493
RD 2024/04/23
AB Liver  failure  is  a  final  common  pathway  for  a  broad  range  of  diagnoses.  In  the  patient  with  liver  failure,  accurate  nutritional  assessment  may  be  complicated  by  fluid  shifts  and  organomegaly.  Nutrition  therapy  in  this  population  can  be  complex  due  to  metabolic  and  electrolyte  derangements.  When  chronic  liver  disease  (CLD)  is  present,  malabsorption  of  fats  and  fat-soluble  vitamins  may  lead  to  multiple  nutritional  deficiencies.  Liver  failure  requiring  admission  to  the  pediatric  intensive  care  unit  (PICU)  can  be  divided  into  2  categories:  acute  liver  failure  (ALF)  and  acute-on-chronic  liver  failure  (ACLF).  Even  during  early  stages  of  disease,  impaired  nutritional  status  has  been  associated  with  poor  clinical  outcome  and  higher  morbidity  and  mortality  in  the  posttransplant  period.1-3  This  chapter  will  review  some  of  the  underlying  causes  of  malnutrition  and  provide  recommendations  for  assessment  and  management  of  nutrition  support  for  patients  with  liver  disease  in  the  PICU  setting.