RT Book, Section A1 Barber, Jessica A1 Bunney, E. Bradshaw A2 Schafermeyer, Robert A2 Tenenbein, Milton A2 Macias, Charles G. A2 Sharieff, Ghazala Q. A2 Yamamoto, Loren G. SR Print(0) ID 1105683601 T1 Anaphylaxis T2 Strange and Schafermeyer's Pediatric Emergency Medicine, 4e YR 2014 FD 2014 PB McGraw-Hill Education PP New York, NY SN 978-0-07-182926-7 LK accesspediatrics.mhmedical.com/content.aspx?aid=1105683601 RD 2024/04/23 AB More than 50% of anaphylaxis cases are idiopathic; therefore, a high index of suspicion is needed to make the diagnosis in children.Airway compromise can occur rapidly.Epinephrine is the first-line medication for the treatment of moderate-to-severe anaphylaxis.In severe anaphylaxis if 2 to 3 fluid boluses (20 cc/kg) are given, as well as epinephrine; if hypotension persists, an epinephrine drip is indicated.