RT Book, Section
A1 Gomella, Tricia Lacy
A1 Cunningham, M. Douglas
A1 Eyal, Fabien G.
A1 Tuttle, Deborah J.
SR Print(0)
ID 1107524438
T1 Lyme Disease
T2 Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e
YR 2013
FD 2013
PB McGraw-Hill Education
PP New York, NY
SN 9780071768016
LK accesspediatrics.mhmedical.com/content.aspx?aid=1107524438
RD 2024/04/25
AB Lyme  disease  was  first  reported  in  1977,  following  an  unusual  cluster  of  adults  and  children  with  oligoarticular  arthritis  in  a  certain  neighborhood  of  Lyme,  Connecticut.  Subsequently,  a  multisystem  disease  was  described  and  attributed  to  the  spirochete  Borrelia  burgdorferi.  Lyme  disease  manifests  as  a  spectrum  of  skin,  musculoskeletal,  cardiac,  and  neurologic  findings.  It  is  a  vector-borne  disease  following  the  bite  of  an  Ixodes  tick—usually  the  black-legged  Ixodes  scapularis,  commonly  known  as  the  deer  tick.  The  species  Ixodes  includes  additional  subspecies  (eg,  I.  pacificus,  I.  dammini,  and  I.  ricinus)  that  contribute  to  a  worldwide  distribution  of  the  disease  and  is  known  to  be  endemic  in  North  and  South  America,  Europe,  Asia,  Africa,  and  Australia.  Prenatal  exposure  to  B.  burgdorferi  and  the  development  of  gestational  borreliosis  can  result  in  maternal  Lyme  disease  with  placentitis  and  transplacental  infection  of  the  fetus  and  newborn.