RT Book, Section
A1 Gomella, Tricia Lacy
A1 Cunningham, M. Douglas
A1 Eyal, Fabien G.
A1 Tuttle, Deborah J.
SR Print(0)
ID 1107524754
T1 Patent Ductus Arteriosus
T2 Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e
YR 2013
FD 2013
PB McGraw-Hill Education
PP New York, NY
SN 9780071768016
LK accesspediatrics.mhmedical.com/content.aspx?aid=1107524754
RD 2024/04/23
AB The  ductus  arteriosus  is  a  large  vessel  that  connects  the  main  pulmonary  trunk  (or  proximal  left  pulmonary  artery)  with  the  descending  aorta,  some  5–10  mm  distal  to  the  origin  of  the  left  subclavian  artery.  In  the  fetus,  it  serves  to  shunt  blood  away  from  the  lungs  and  is  essential  (closure  in  utero  may  lead  to  fetal  demise  or  pulmonary  hypertension).  In  full-term  healthy  newborns,  functional  closure  of  the  ductus  occurs  rapidly  after  birth.  Final  functional  closure  occurs  in  almost  half  of  full-term  infants  by  24  hours  of  age,  in  90%  by  48  hours,  and  in  all  by  96  hours  after  birth.  Patent  ductus  arteriosus  (PDA)  refers  to  the  failure  of  the  closure  process  and  continued  patency  of  this  fetal  channel.