RT Book, Section A1 Gomella, Tricia Lacy A1 Cunningham, M. Douglas A1 Eyal, Fabien G. A1 Tuttle, Deborah J. SR Print(0) ID 1107524965 T1 Retinopathy of Prematurity T2 Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e YR 2013 FD 2013 PB McGraw-Hill Education PP New York, NY SN 9780071768016 LK accesspediatrics.mhmedical.com/content.aspx?aid=1107524965 RD 2024/03/29 AB Retinopathy of prematurity (ROP). A disorder of the developing retinal vasculature resulting from interruption of normal progression of newly forming retinal vessels. Vasoconstriction and obliteration of the advancing capillary bed are followed in succession by neovascularization extending into the vitreous, retinal edema, retinal hemorrhages, fibrosis, and traction on, and eventual detachment of, the retina. In most cases, the process is reversed before fibrosis occurs. Advanced stages may lead to blindness.Retrolental fibroplasia (RLF). As originally described, the condition was seen only in its most advanced form, after extensive fibrosis and scarring had already occurred behind the lens. It was, therefore, termed retrolental fibroplasia. It is now understood that recognizable changes occur in the developing vasculature before end-stage fibrosis occurs, making this condition a true retinopathy. Because it is found chiefly in premature infants, it is called retinopathy of prematurity.Cicatricial ROP. The term cicatricial ROP refers to fibrotic disease.