RT Book, Section A1 Gomella, Tricia Lacy A1 Cunningham, M. Douglas A1 Eyal, Fabien G. A1 Tuttle, Deborah J. SR Print(0) ID 1107527613 T1 Venous Access: Venipuncture (Phlebotomy) T2 Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e YR 2013 FD 2013 PB McGraw-Hill Education PP New York, NY SN 9780071768016 LK accesspediatrics.mhmedical.com/content.aspx?aid=1107527613 RD 2024/04/24 AB Note: Cochrane review states that venipuncture, by a skilled operator, is the method of choice for blood sampling in term infants. It was found to be less painful than heelstick sampling and a more effective sampling method. To obtain a blood sample for routine analysis or blood culture. Venipuncture typically allows a larger volume of blood (recommended if ≥1 mL needed) to be collected and is the method of choice for obtaining blood cultures. It is preferred over capillary blood sampling for certain tests (drug levels, hemoglobin/hematocrit, karyotype, coagulation studies, cross-matching blood, and ammonia, lactate, and pyruvate). Arterial blood is preferred for lactate, pyruvate, and ammonia.To obtain a central hematocrit. Venipuncture is more reliable than heelstick.Administer medications.Venous blood gas. This can be used in some diseases (neonatal sepsis/respiratory distress syndrome [RDS]) to diagnose acid-base imbalance if an arterial blood gas can't be obtained. Although arterial blood gas is preferred, venous samples show good validity in terms of pH, Pco2, and HCO3.