RT Book, Section A1 Gomella, Tricia Lacy A1 Cunningham, M. Douglas A1 Eyal, Fabien G. A1 Tuttle, Deborah J. SR Print(0) ID 1107527871 T1 Hyponatremia T2 Neonatology: Management, Procedures, On-Call Problems, Diseases, and Drugs, 7e YR 2013 FD 2013 PB McGraw-Hill Education PP New York, NY SN 9780071768016 LK accesspediatrics.mhmedical.com/content.aspx?aid=1107527871 RD 2024/04/19 AB An infant has a serum sodium of 127 mEq/L, below the normal accepted value of 135 mEq/L. The incidence of hyponatremia is greater than hypernatremia in premature infants. Evidence now shows it is a serious condition in very preterm infants (<33 weeks' gestation), who have large variations of the serum sodium concentration, as they are at risk for poor neuromotor outcome at 2 years. Preterm infants with an increased risk of hyponatremia from sodium restriction show impaired growth and worse neurodevelopment at 10–13 years of age. Hyponatremia is also a risk factor for sensorineural hearing loss, intracranial hemorrhage, and cerebral palsy. Hyponatremia in infants who experienced perinatal birth asphyxia are at risk for an increased mortality.