RT Book, Section
A1 Volz, Holly H.
A1 Usatine, Richard P.
A2 Usatine, Richard P.
A2 Sabella, Camille
A2 Smith, Mindy Ann
A2 Mayeaux, E.J.
A2 Chumley, Heidi S.
A2 Appachi, Elumalai
SR Print(0)
ID 1114877260
T1 Chronic Bullous Disease of Childhood
T2 The Color Atlas of Pediatrics
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-176701-9
LK accesspediatrics.mhmedical.com/content.aspx?aid=1114877260
RD 2024/04/19
AB An  8  year-old  girl  presented  with  a  two-day  history  of  blisters  on  her  face,  trunk,  and  extremities  (Figure  155-1).  She  complained  of  moderate  discomfort  from  the  blisters,  but  denied  itching,  burning,  fever,  and  recent  illness.  She  was  not  taking  any  medications.  Biopsy  demonstrated  subepidermal  vesicles  and  a  rich  neutrophilic  infiltrate  in  the  dermal  papillary  tips.  Direct  immunofluorescence  revealed  a  linear  deposition  of  IgA  along  the  basement  membrane  confirming  the  diagnosis  of  chronic  bullous  disease  of  childhood.The  patient  was  started  on  systemic  therapy  with  dapsone  and  her  lesions  quickly  resolved.