RT Book, Section
A1 Raman, Vidya
A1 Mayeaux, E.J.
A2 Usatine, Richard P.
A2 Sabella, Camille
A2 Smith, Mindy Ann
A2 Mayeaux, E.J.
A2 Chumley, Heidi S.
A2 Appachi, Elumalai
SR Print(0)
ID 1114878164
T1 Lupus—Systemic and Cutaneous
T2 The Color Atlas of Pediatrics
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-176701-9
LK accesspediatrics.mhmedical.com/content.aspx?aid=1114878164
RD 2024/04/25
AB A  previously  healthy  16-year-old  African  American  girl  presented  to  the  clinic  with  alopecia  and  rash  over  her  face  and  arms  for  6  months  (Figures  173-1  and  173-2).  She  reported  pain  in  her  knees  and  ankles  for  a  year  and  an  oral  ulcer  3  months  ago,  which  had  healed.  Laboratory  evaluation  was  remarkable  for  a  low  white  blood  cell  count  at  2.4  ×  1000/uL  (normal  5.0–13.0  ×  100/uL),  hemoglobin  of  10.8  g/dL  (normal  11.8–16.0  g/dL),  and  platelet  count  of  109  ×  1000/uL  (normal  142–424  ×  1000/uL).  Erythrocyte  sedimentation  rate  was  elevated  at  45  mm/hr  (normal  0–15  mm/hr).  Antinuclear  antibody  was  positive  at  1:640  with  a  strongly  positive  antidouble  stranded  DNA  antibody  confirming  a  diagnosis  of  systemic  lupus  erythematosus  (SLE).  Urinalysis  did  not  show  proteinuria  to  suggest  renal  involvement.  She  was  treated  with  prednisone  and  hydroxychloroquine  resulting  in  improvement  in  her  problems.