RT Book, Section
A1 Greiwe, Justin
A1 Dückers, Gregor
A1 Niehues, Tim
A1 Schroer, Brian
A2 Usatine, Richard P.
A2 Sabella, Camille
A2 Smith, Mindy Ann
A2 Mayeaux, E.J.
A2 Chumley, Heidi S.
A2 Appachi, Elumalai
SR Print(0)
ID 1114880569
T1 Chronic Granulomatous Disease
T2 The Color Atlas of Pediatrics
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-176701-9
LK accesspediatrics.mhmedical.com/content.aspx?aid=1114880569
RD 2024/04/23
AB A  4-year-old  boy  presents  with  a  recent  history  of  persistent  pneumonia.  A  detailed  past  medical  history  reveals  several  recurrent  infections  including  pneumonia  and  lymph  node  abscesses  growing  Staphylococcus  aureus  and  Burkholderia  cepacia.  His  parents  claim  that  he  has  been  prescribed  multiple  courses  of  antibiotics  over  the  last  month  with  no  improvement  in  his  respiratory  symptoms.  There  is  no  family  history  of  immunodeficiency.  Examination  of  the  child  revealed  mild  subcostal  retractions  and  diffuse  rales  bilaterally.  A  chest  x-ray  demonstrated  bilateral  infiltrates  of  the  upper  and  middle  lung  fields  and  a  CT  showed  multifocal  pneumonia  (Figure  220-1).  Diagnostic  bronchoalveolar  lavage  and  serological  tests  confirmed  the  presence  of  invasive  pulmonary  aspergillosis  and  the  patient  was  placed  on  appropriate  antifungal  treatment.  Because  of  the  history  and  types  of  infection,  a  work-up  for  immunodeficiency  was  undertaken  and  the  child  was  found  to  have  chronic  granulomatous  disease.