RT Book, Section
A1 Wells, Robert G.
SR Print(0)
ID 1148948625
T1 Congenital Abnormalities of the Brain
T2 Diagnostic Imaging of Infants and Children
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071808392
LK accesspediatrics.mhmedical.com/content.aspx?aid=1148948625
RD 2024/09/12
AB The  spectrum  of  congenital  brain  malformations  is  complex  and  classification  schemes  are  imperfect.  Neuroimaging  evaluations  provide  extensive  information  concerning  abnormal  brain  morphology  and  cellular  organization.  Correlation  of  this  information  with  well-established  concepts  of  normal  embryological  and  fetal  neural  development  provides  a  conceptual  framework  for  a  greater  understanding  of  brain  anomalies.  The  most  frequently  utilized  neuroimaging  classification  scheme  for  congenital  malformations  of  the  brain  recognizes  4  major  types  that  correlate  to  stages  of  development:  (1)  dorsal  induction  (primary  neurulation),  (2)  ventral  induction  (telencephalization),  (3)  neuronal  proliferation,  differentiation,  and  histogenesis,  and  (4)  neuronal  migration.  It  is  important  to  recognize,  however,  that  this  system  is  an  oversimplification  of  a  heterogeneous  and  complex  group  of  disorders.