RT Book, Section
A1 Wells, Robert G.
SR Print(0)
ID 1148948913
T1 Intracranial Infections
T2 Diagnostic Imaging of Infants and Children
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071808392
LK accesspediatrics.mhmedical.com/content.aspx?aid=1148948913
RD 2024/04/19
AB Congenital  infections  are  acquired  by  the  maternal  hematogenous-transplacental  route  or  by  exposure  to  organisms  during  passage  through  the  birth  canal.  Most  fetal  bacterial  infections  are  due  to  the  ascent  of  organisms  from  the  cervix  into  the  amniotic  fluid.  Congenital  infections  of  the  central  nervous  system  (CNS),  however,  are  usually  transmitted  transplacentally.  The  TORCH  organisms  cause  most  of  these  CNS  infections:  Toxoplasma,  other  (coxsackievirus,  syphilis,  varicella-zoster,  human  immunodeficiency  virus,  and  parvovirus  B19),  rubella,  cytomegalovirus,  and  herpes  simplex  virus  type  2  (HSV).  These  organisms  can  cause  chorioretinitis,  microcephaly,  and  focal  cerebral  calcification.