RT Book, Section A1 Le Pichon, Jean-Baptiste A1 Shapiro, Steven M. A2 Stevenson, David K. A2 Cohen, Ronald S. A2 Sunshine, Philip SR Print(0) ID 1109792479 T1 Neonatal Hypotonia T2 Neonatology: Clinical Practice and Procedures YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071763769 LK accesspediatrics.mhmedical.com/content.aspx?aid=1109792479 RD 2024/03/29 AB It is difficult to find any reference to neonatal hypotonia before the beginning of the 20th century. This may be in part related to the very high infant mortality rate and the fact that for most of history children were not considered of much value until they had reached the age of 7 or so, when they had survived the vicissitudes of childhood and could start working.1 With the advent of the Industrial Revolution and the fundamental changes in medicine that accompanied it, the first reports of infantile hypotonia were published (for an excellent summary of this history, refer to Victor Dubowitz’s seminal work on the floppy infant2). Since the 1970s, and likely as a result of the exponential improvements in diagnostic tools, the scientific publications dedicated to hypotonia have steadily accumulated (Figure 17-1).