RT Book, Section A1 Ohls, Robin K. A1 Bishara, Nader A1 Wong, Wendy A1 Glader, Bertil A2 Stevenson, David K. A2 Cohen, Ronald S. A2 Sunshine, Philip SR Print(0) ID 1109793925 T1 Anemia in the Neonatal Period T2 Neonatology: Clinical Practice and Procedures YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071763769 LK accesspediatrics.mhmedical.com/content.aspx?aid=1109793925 RD 2024/09/09 AB The newborn period marks a time when red blood cell (RBC) indices change significantly. Anemia can occur at various times in the neonatal period, from the perinatal and immediate postnatal period through the first months of life. Hematocrits 2 or more standard deviations below the normal range for gestation are seen frequently and should be evaluated. Conversely, true anemia, the inability to adequately deliver oxygen to tissues, is less common. Anemia can be classified into the following 3 major processes: hemolysis, hemorrhage, or hypoproliferative disease. Anemia can also result from overlapping processes. For example, sepsis can result in hemolysis, disseminated intravascular coagulation (DIC), and subsequent hemorrhage. This chapter reviews fetal and neonatal erythropoiesis, discusses the etiology and diagnosis of anemia in the neonatal period, and offers management options for anemic term and preterm infants.