RT Book, Section A1 Kastenberg, Zachary A1 Dutta, Sanjeev A2 Stevenson, David K. A2 Cohen, Ronald S. A2 Sunshine, Philip SR Print(0) ID 1109794322 T1 Gastroschisis and Omphalocele T2 Neonatology: Clinical Practice and Procedures YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071763769 LK accesspediatrics.mhmedical.com/content.aspx?aid=1109794322 RD 2024/03/28 AB Gastroschisis and omphalocele (also referred to as exomphalos) are 2 of the most common abdominal wall defects requiring neonatal intensive care. Their similarities, most notably evisceration of abdominal structures through a defect at or near the umbilicus, misled generations of physicians and surgeons to inaccurately diagnose them as a single common disease. The pathologic differences between these 2 entities were formally realized when, in 1953, Thomas Moore and George Stokes defined gastroschisis as a large extraumbilical evisceration of intestines without a covering sac. They distinguished this from omphalocele, which was defined as the herniation of viscera into the base of the umbilical cord with a protective membranous sac.1 The establishment of gastroschisis and omphalocele as 2 distinct pathologies with their own specific anatomic features and associated anomalies provides the basis for our management of these defects today.