RT Book, Section A1 Lau, Yu-Lung A1 Lee, Pamela A2 Stevenson, David K. A2 Cohen, Ronald S. A2 Sunshine, Philip SR Print(0) ID 1109795924 T1 Thymic Aplasia and T-Cell Disorder T2 Neonatology: Clinical Practice and Procedures YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071763769 LK accesspediatrics.mhmedical.com/content.aspx?aid=1109795924 RD 2024/04/19 AB As detailed in chapter 49, host defense mechanisms against pathogens are defective in the newborn as a result of immature immunity. Preterm infants are particularly vulnerable to infections associated with prematurity-related complications and medical interventions. The recognition of inborn errors of immunity and differentiation from functional immaturity of the immune system pose a diagnostic challenge. An organized clinical approach is essential to facilitate early diagnosis, which has a significant impact on prognosis and survival.