RT Book, Section A1 Mickas, Nick A2 Stevenson, David K. A2 Cohen, Ronald S. A2 Sunshine, Philip SR Print(0) ID 1109798327 T1 Mechanical Ventilation T2 Neonatology: Clinical Practice and Procedures YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071763769 LK accesspediatrics.mhmedical.com/content.aspx?aid=1109798327 RD 2024/04/19 AB The goal of mechanical ventilation, as for any respiratory support, is simply to achieve adequate gas exchange to maintain physiologic neutrality. Mechanical ventilation is indicated when noninvasive forms of respiratory support such as nasal continuous positive airway pressure (NCPAP) are inadequate to support the infant’s respiratory needs. This may manifest as hypoxia, hypercarbia, or apnea. Far less-common indications for mechanical ventilation include airway anomalies and central or pharmacologically induced apnea. Mechanical ventilation of the neonate can seem intimidating to even the most seasoned practitioner. This chapter provides a systematic approach to management of the ventilated neonate, addressing the basic physiology underlying neonatal pulmonary pathology.