RT Book, Section A1 Lanpher, Brendan A1 Summar, Marshall A1 Batshaw, Mark L. A2 Stevenson, David K. A2 Cohen, Ronald S. A2 Sunshine, Philip SR Print(0) ID 1109799248 T1 Neonatal Hyperammonemia T2 Neonatology: Clinical Practice and Procedures YR 2015 FD 2015 PB McGraw-Hill Education PP New York, NY SN 9780071763769 LK accesspediatrics.mhmedical.com/content.aspx?aid=1109799248 RD 2024/10/04 AB Neonatal hyperammonemia is a feature of many different inborn errors of metabolism that may be individually rare but have about a 1:5000 cumulative incidence.1,2 It can also be a feature of fulminant liver failure of any cause and of structural anomalies leading to portosystemic shunting. Neonatal hyperammonemia represents a true metabolic emergency as rapid identification and intervention are critical to a positive neurologic outcome. It is essential that neonatal centers have a protocol and plan in place to address these patients. A representative protocol is provided in this chapter (Table 106-1) and details are provided.