RT Book, Section
A1 Jenks, Jennifer
A1 Nadeau, Kari
A2 Stevenson, David K.
A2 Cohen, Ronald S.
A2 Sunshine, Philip
SR Print(0)
ID 1109799522
T1 Severe Combined Immunodeficiency (SCID)
T2 Neonatology: Clinical Practice and Procedures
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071763769
LK accesspediatrics.mhmedical.com/content.aspx?aid=1109799522
RD 2022/05/19
AB Severe  combined  immunodeficiency  (SCID)  is  a  fatal  primary  immune  condition  characterized  by  the  absence  of  both  humoral  and  cellular  immunity  with  severe  lymphopenia.  Patients  with  SCID  have  reduced  numbers  and  function  of  both  T  and  B  lymphocytes  (and  in  some  cases,  natural  killer  [NK]  cells)  and  hypogammaglobulinemia.  If  left  untreated,  babies  with  SCID  most  often  die  within  1  to  2  years  of  life  because  of  severe,  recurrent  infections.